Alexandria Journal of Science and Technology is an interdisciplinary journal. The Journal publishes one Volume divided into two Issues per Year (one in January and the second in July). The Editor-in-Chief and publisher work in tandem to execute the plan that was set for the journal. The publisher provides the editors with tools and training to assist them in their important role. Each main Research Field has a Managing Editor, who is responsible of the corresponding Research Topics.

Manuscripts are evaluated on the basis that they present new insight into the investigated topic and are likely to contribute to research progress. It is understood that all authors listed on a manuscript have agreed to its submission. The signature of the corresponding author on the letter of submission signifies that these conditions have been fulfilled. Received manuscripts will initially be examined by the AJST editorial office and those deemed to have insufficient grounds for publication may be rejected without external evaluation. Manuscripts not prepared in the advised style described will be sent back to authors for correction. The authors will be notified with the reference number once the manuscript has been assigned to an Editor. The assigned manuscripts will be sent to 2-3 independent experts for scientific evaluation. The evaluation process commonly takes an average of 6 weeks.

Peer reviewers may make a recommendation about an article, but it is the editor who has the ultimate responsibility to make a final decision on whether to accept or reject an article for publication in a journal. 3 reviewers are invited for manuscript reviewing. At least 2 reviewers should accept or reject the manuscript in order to make a final decision. In case of only one acceptance, another reviewer will be invited.

Editors are not involved in decisions about papers that they have written themselves or have been written by family members or colleagues or which relate to products or services in which the editor has an interest. Any such submission is subject to all of the journal's usual procedures, with peer review handled independently of the relevant editor and their research groups.